Newest publications
Association between vitamin D status and eryptosis - results from the German National Cohort Study
(2023) Ewendt, Franz; Schmitt, Marvin; Kluttig, Alexander; Kühn, Julia; Hirche, Frank; Kraus, Frank B.; Ludwig-Kraus, Beatrice; Mikolajczyk, Rafael; Wätjen, Wim; Bürkner, Paul-Christian; Föller, Michael; Stangl, Gabriele I.; Ewendt, Franz; Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany; Schmitt, Marvin; Cluster of Excellence SimTech, University of Stuttgart, Stuttgart, Germany; Kluttig, Alexander; Institute of Medical Epidemiology, Biostatistics, and Informatics, Medical Faculty of the Martin Luther University Halle-Wittenberg, Halle (Saale), Germany; Kühn, Julia; Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany; Hirche, Frank; Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany; Kraus, Frank B.; Central Laboratory, Department of Laboratory Medicine, University Hospital Halle, Halle (Saale), Germany; Ludwig-Kraus, Beatrice; Central Laboratory, Department of Laboratory Medicine, University Hospital Halle, Halle (Saale), Germany; Mikolajczyk, Rafael; Institute of Medical Epidemiology, Biostatistics, and Informatics, Medical Faculty of the Martin Luther University Halle-Wittenberg, Halle (Saale), Germany; Wätjen, Wim; Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany; Bürkner, Paul-Christian; Cluster of Excellence SimTech, University of Stuttgart, Stuttgart, Germany; Föller, Michael; Department of Physiology, University of Hohenheim, Stuttgart, Germany; Stangl, Gabriele I.; Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany
Vitamin D, besides its classical effect on mineral homeostasis and bone remodeling, can also modulate apoptosis. A special form of apoptosis termed eryptosis appears in erythrocytes. Eryptosis is characterized by cell shrinkage, membrane blebbing, and cell membrane phospholipid disorganization and associated with diseases such as sepsis, malaria or iron deficiency, and impaired microcirculation. To our knowledge, this is the first study that linked vitamin D with eryptosis in humans. This exploratory cross-sectional trial investigated the association between the vitamin D status assessed by the concentration of plasma 25-hydroxyvitamin D (25(OH)D) and eryptosis. Plasma 25(OH)D was analyzed by LC–MS/MS, and eryptosis was estimated from annexin V-FITC-binding erythrocytes by FACS analysis in 2074 blood samples from participants of the German National Cohort Study. We observed a weak but clear correlation between low vitamin D status and increased eryptosis ( r = − 0.15; 95% CI [− 0.19, − 0.10]). There were no differences in plasma concentrations of 25(OH)D and eryptosis between male and female subjects. This finding raises questions of the importance of vitamin D status for eryptosis in terms of increased risk for anemia or cardiovascular events.
Valorization for biodiversity and ecosystem services in the agri-food value chain
(2023) Voglhuber-Slavinsky, Ariane; Lemke, Nahleen; MacPherson, Joseph; Dönitz, Ewa; Olbrisch, Mathias; Schöbel, Philipp; Moller, Björn; Bahrs, Enno; Helming, Katharina; Voglhuber-Slavinsky, Ariane; Institute of Farm Management, University of Hohenheim, Stuttgart, Germany; Lemke, Nahleen; Leibniz Centre for Agricultural Landscape Research (ZALF), Müncheberg, Germany; MacPherson, Joseph; Leibniz Centre for Agricultural Landscape Research (ZALF), Müncheberg, Germany; Dönitz, Ewa; Fraunhofer Institute for Systems and Innovation Research ISI, Competence Center Foresight, Karlsruhe, Germany; Olbrisch, Mathias; Chair of Public Law, Administrative, European, Environmental, Agricultural and Food Law, Prof. Dr. Ines Härtel, European University Viadrina Frankfurt (Oder) | Research Center for Digital Law, Frankfurt (Oder), Germany; Schöbel, Philipp; Chair of Public Law, Administrative, European, Environmental, Agricultural and Food Law, Prof. Dr. Ines Härtel, European University Viadrina Frankfurt (Oder) | Research Center for Digital Law, Frankfurt (Oder), Germany; Moller, Björn; Fraunhofer Institute for Systems and Innovation Research ISI, Competence Center Foresight, Karlsruhe, Germany; Bahrs, Enno; Institute of Farm Management, University of Hohenheim, Stuttgart, Germany; Helming, Katharina; Faculty of Landscape Management and Nature Conservation, University for Sustainable Development (HNEE), Eberswalde, Germany
This article defines the term valorization of biodiversity and ecosystem services (BES) measures, as distinguished from their valuation, and underpins it with an assessment of private valorization examples along the agri-food value chain. Valorization incentivizes measures for promoting BES, while valuation refers to its quantification. Valuation can be a step of valorization but is not indispensable. In scientific literature, the terms valorization and valuation are often used interchangeably. In addition, there is a lack of research on private options versus conventional, public policy options. Therefore, we searched for private valorization options primarily in public sources (gray literature and websites). This led to the identification of four clusters (markets for voluntary services, labeling, and certification, environmental management/CSR, and tradable permits and quotas). Based on these clusters the options were assessed from a legal and systems dynamics perspective. In addition, the viability of selected valorization options in different future scenarios was examined. The analysis revealed a wide range of private valorization options, which in contrast to public policy options that focus almost entirely on the production stage, are spread across the agri-food value chain. Their suitability differs under different future scenarios, legal and systems conditions.
Der Pilot auf dem Acker : eine Regelhydraulik für Hanomag-Traktoren
(2015) Sellschopp, Oskar