Browsing by Subject "Futteraufnahme"

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Adaptation of herd simulation models to predict the efficiency of the use of resources in tropical ruminant production systems
(2020) Bateki Adjogo, Christian; Dickhöfer, Uta
Agricultural systems in the (Sub-)Tropics are under increasing pressure to produce more food and satisfy the growing demand of a rapidly growing and more affluent human population for agricultural products. With growing rates of urbanization in these regions and the associated dietary changes, the demand for calories from animal-based foods like milk, meat, and eggs could increase by 74 to 114 % between 2010 and 2050. Ruminant livestock have the potential to contribute to satisfying the demand for animal-based foods in the (Sub-)Tropics, but also raise considerable environmental concerns, amongst others due to their emissions. The use of simulation models is a holistic approach to identify how to sustainably harness the potential of ruminants for animal-based food production in the (Sub-)Tropics. Although several ruminant herd models are relevant for studying tropical ruminant production systems, most of them were developed using data that quantify and characterize biological processes of ruminants in temperate regions. Therefore, the present thesis identified and adapted an existing ruminant livestock herd model to adequately predict resource use and the potential outputs from production systems in the (Sub-)Tropics. The present thesis showed that state-of-the-art ruminant livestock herd models used to simulate tropical production systems need further development to enable them to address the modelling needs identified. Instead of developing new models to address these modelling needs, existing simulation models could be adapted using the increasingly available data that quantify and characterize biological processes in ruminants in these regions. This approach will ensure that not only the direction of change for different management strategies will be identified for tropical ruminant production systems, but also the correct magnitude of resources use and productive and reproductive performance.
Comparison of plant cell wall degrading community in the rumen of N’Dama and N’Dama x Jersey crossbred cattle in relation to in vivo and in vitro cell wall degradation
(2004) Nouala-Fonkou, Simplice; Becker, Klaus
This thesis presents a unique combination of an in vivo feeding trial, the analysis of the microbial community structure in the rumen, and in vitro fermentation studies, in order to assess the impact of breeds and diets on animal performance in a West African production setting. Pure N?Dama and N?Dama x Jersey crossbred cattle were fed two basal diets, baby corn and groundnut hay, supplemented with graded levels of either conventional concentrate or moringa leaf meal, to compare animal responses in productivity. In this context, Moringa oleifera leaf meal constitutes a locally available, potential alternative to commercial concentrate for cattle production. The cell wall digesting community of N?Dama and its crosses was analysed using phylogenetically based hybridisation probes to account for the contribution of rumen microbes to differences in fermentation patterns and animal response. In vitro fermentation studies were carried out using the same diets and supplementation levels as fed in vivo, to test the accuracy of the in vitro gas production technique in predicting the optimum level of supplementation. The in vivo feeding experiment focussed on the comparison of breed performance with diets relevant for local production conditions. Six N?Dama and six N?Dama x Jersey (crossbred) animals were used in a cross over design. They were fed consecutively three combinations of roughage and supplement, baby corn stover and concentrate (BCS:Co), groundnut hay and concentrate (GNH:Co) and groundnut hay and moringa meal (GNH:Mo), each at 5 levels of supplementation (0, 10, 20, 30 and 40%). Results from this study showed that there was a clear difference in animal response to different feeding regimes between the two breeds. When averaged over all diets organic matter intake (OMI) was higher in crossbred compared to N?Dama (94 and 87.6 g/kg 0.75 d-1, respectively). When analyzed for the diets and averaged over the breeds OMI was higher when animals were fed the baby corn based diet compared to groundnut based diets (95 against 88 g/kg 0.75 d-1). Only when the diet consisted of BCS:Co, and at low levels of supplementation, N?Dama ingested more than crossbred, but the difference was not significant. With GNH:Co crossbred ingested significantly more at levels of supplementation less or equal to 20%. With GNH:Mo crossbred ingested more, whatever the level of supplementation. The optimum level of supplementation in vivo, estimated with the single slope broken line model, was 10% and 20% for both breeds when they were fed BCS:Co and GNH:Co respectively, but 30% for N?Dama and 10% for the crossbreds when animals were fed GNH:Mo. Organic matter digestibility (OMD) was higher in N?Dama (64.6% against 60.7% in crossbreds) when animals were fed BCS:Co and supplementation had no effect on OMD of BCS:Co whatever the breed. When animals were fed groundnut hay as basal diet, OMD was also significantly higher in N?Dama at low levels of supplementation, but the differences became insignificant beyond 10% and 20% of concentrate or moringa, respectively. With GNH:Co OMD showed a quadratic response (p<0.001) with increasing level of supplementation when it was fed to crossbreds and was not affected when it was fed to N?Dama. Increasing levels of moringa meal supplementation increased OMD in both breeds up to a peak at 20 and 30% for N?Dama and crossbred, respectively. Average daily weight gain (ADG) was not affected by the breed, however it was higher on BCS:Co compared to other diets. On BCS:Co ADG increased with the level of supplementation, reaching a peak at 30%, whereas supplementation had no effect on ADG when animals were fed groundnut hay based diets. As N?Dama could take in and digest more of the low quality BCS:Co diet, they were less efficient in feed conversion under this feeding regime (FCE: 14 vs. 9 for the crossbreds). On GNH based diets, however, N?Dama surpassed the crossbreds in feed conversion efficiency with ratios of 11 vs. 13 for GNH:Co and 9 vs. 27 on GNH:Mo. Rumen microbes play the key role for the digestibility of a given feed and thus also for feed intake and finally animal performance. Obviously, the community composition and activity is highly dependent on the diet. With the present set-up, however, with identical external conditions and three different, well defined diets fed to both, N?Dama and crossbred cattle, a comparison of the microbial community structure between breeds could be attempted. The in vivo and in vitro data taken in the other parts of the study allow a sensible interpretation of potential changes in microbial composition. Rumen fluid was collected from three fistulated N?Dama and three crossbred animals adapted to the experimental diets at medium supplementation level. The cell wall degrading community was analyzed using the phylogenetically based 16S rRNA hybridisation probes. The results showed that on BCS:Co diet the Fibrobacter and R. flavefaciens RNA concentrations were higher in rumen fluid of N?Dama compared to crossbred. These concentrations were also significantly affected by the diet, such that they were higher on baby corn stover compared to groundnut hay based diets. The results of the microbial community analysis suggested that the differences between breeds observed in digestibility could be partially explained by the composition of the cell wall degrading community. Parallel to the in vivo experiment, in vitro fermentation studies were undertaken to evaluate the predictability of the in vivo response to supplementation by the in vitro data. Rumen fluid from 3 N?Dama and 3 crossbred donor animals was used for 24 hour in vitro fermentations. The donor animals were fed consecutively the same three diets used in vivo (BCS:Co, GNH:Co and GNH:Mo) at 20% level of supplementation. Each of these inocula was incubated with in vitro substrates consisting of all the combinations tested in vivo (i.e. 3 diets, 5 levels of supplementation) plus supplement alone. This design should allow to analyze for both, the impact of donor breed as well as that of the donor diet and to conclude which factors may be varied while maintaining predictability. The breed of the donor animals did not significantly affect 24 hour gas production, but short chain fatty acid concentration was higher with rumen fluid from crossbreds when donors were fed BCS:Co and GNH:Mo. Moringa meal as supplement to donor animals changed the fermentation pattern of all the substrates, such that gas production and SCFA increased substantially in groundnut hay based substrates, whereas gas production of BCS:Co substrates decreased and SCFA did not substantially change. In vitro digestibility was higher with rumen fluid from N?Dama whatever the diet of donor animals and the substrate incubated. GNH:Mo as donor diet also increased IVTD of all the substrates. Even though there was no clear response in vivo, this indicates a general stimulation of microbial activity in the rumen and renders moringa leaf meal a promising supplement. Averaged over all data there was a positive correlation (r2=0.53 p<0.001) between IVTD and in vivo OMD. This correlation was much stronger when calculated for a specific diet (e.g. r2=0.90 p<0.001 for BCS:Co, averaged over the breeds). Analyzing the data for the individual breeds affected correlations only to a minor degree. Thus, when testing a supplementation strategy in vitro, it should be important that donor animals are fed the same components (roughage and supplement) that will be combined at different levels in vitro, whilst the breed of donor animals may be of second importance. This work provides conclusive evidence that in vitro incubations may be used to design supplementation strategies, thus reducing the need for in vivo experiments. Moringa leaf meal is a promising local resource to substitute for conventional concentrate. Differences in productivity between breeds could be correlated to (and may be partially manifested through) a divergent community structure of rumen microbes. That, in turn, indicates that animals of different breeds might have a ?genetic background? that favours the establishment of a certain community, even if the animals are kept under identical conditions. This relationship should be investigated by more advanced molecular techniques.
Die Regulation der Futteraufnahme beim Schwein - Untersuchung der Wirkungen eines Serotonin Noradrenalin Wiederaufnahmehemmers (Sibutramin) und eines MCH-R1 Antagonisten (Compound B4)
(2007) Sommer, Torsten; Claus, Rolf
The regulation of food- and feed intake is a highly topical investigative area in animal husbandry as well as in human medicine. Here the focus of medicine is primarily on the reduction of food intake and at the same time change of the metabolism to increased energy expenditure in order to counteract the rising number of adiposity and metabolic syndrome. Therefore, substances from pharmacological research are known which act in different nuclei of the hypothalamus and control food intake and energy expenditure. In the present study two of these new substances were examined with regards to their impact on pigs. The results lead to a more detailed understanding of the corresponding mechanisms in pigs, one of the most important animals used in agriculture. In addition, the pig is also a suitable model for human pharmacological research, as it equals the human physiological regulation more than the rat, which is the most common animal model. Study work flow: Two different regulative substances were examined, on the one hand a serotonin noradrenalin reuptake inhibitor (Sibutramine) and on the other hand, a melanin concentrating hormone receptor antagonist (MCH-R1 antagonist; Compound B4). For the evaluation of the effectiveness the following factors were measured; feed intake, water consumption, weight gain, feed conversion rate and the development of body fat content. The changes caused in the regulation of the metabolism were evaluated by anabolic (Growth hormone and IGF-I) and catabolic (cortisol and aldosterone) hormones. In addition, thyroid hormones and urea in the blood plasma were measured as a parameter of protein turnover. The study was divided in three trials, each of them taking six weeks. During the first trial sibutramine was given per os to three animals and three animals were kept as control. During the second trial sibutramine was given intravenously to two animals and two animals were kept as control. During the third trial the MCH-R1 antagonist, Compound B4, was given per os to six animals. The results are described in the following sections. Results of the sibutramine application: The pharmacological effectiveness of sibutramine is mainly explained through its metabolites (desmethyl sibutramine and didesmethyl sibutramine). It was found that for the per os intake of 20 mg/kg LW sibutramine, as well as sibutramine as the first metabolite desmethyl-sibutramine, a lower concentration in the blood plasma existed compared to the intravenous application. Whereas concentration of the second metabolite didesmethyl-sibutramine was higher for per os application than for intravenous application. Since the effectiveness of sibutramine is mainly based on its second metabolite didesmethyl-sibutramine, the way of application was crucial for its effectiveness. This means that the intravenous application was ineffective. After per os application feed intake was significantly reduced, also dependent on the dose applied, but did not lead to a reduced weight gain of the animals. Further, no impact was found on the feed conversion ratio. In contrast, the treatment with sibutramine per os led to significantly increased water consumption. The application of sibutramine had no impact on the growth hormone secretion. However, IGF-1 concentration was increased while feed intake was decreased. The cortisol concentration in blood plasma was not impacted by any treatment. Results of the application of the MCH-R1 antagonist (Compound B4): The application of the antagonist led to a significant reduction of feed intake, dependent on the dose applied. The means derived for daily weight gain show considerable individual differences per animal, hence the reduction of daily weight gain overall was not significant. Further, changes in water consumption were also detected in this trial. However, it could not be clarified if this was caused by the application of the antagonist or the reduced feed intake. Generally, the application of Compound B4 tends to result in energy saving mechanisms, which have an impact on metabolic active hormones. IGF-1 for example, was slightly lower in the control phase. Neither sibutramine nor the MCH-R1 antagonist Compound B4 had any impact on the concentration of thyroid hormones or cortisol. Conclusions: The studies have shown that the MCH-R1 antagonist leads to a significant reduction of feed intake in pigs, whereas the metabolic active hormones, and therefore the energy expenditure, do not seem to be impacted at all. In addition, it was proven that the pig is a useful animal model for such human pharmacological investigations. However, the large amount of substances required can be seen as disadvantageous and as a limiting factor in the investigation of new agents with an initially small amount of substance synthesis.
Untersuchungen zur Variation und Rhythmik der individuellen Futteraufnahme bei Pekingenten in Gruppenhaltung
(2003) Bley, Tobias Alexander Georg; Bessei, Werner
Methods to record feed intake in group reared individuals were only available for larger domestic species, such as pigs and cattle. Similar equipment for ducks using an antenna-receiver system had to be developed for the present study. The antenna was fitted nearby the feeder and the transponder was attached to the wing mark. The feeders were connected to an electronic scale and the following characteristics were recorded by a PC continuously: number of the bird, day, time of day, time of visits to the feeder, feed consumption. The system was suitable for duckling from 14 days old onwards. Two experiments were carried out. In experiment 1 a total of 50 male Pekin-type hybrid from 14 to 49 days of age were used. In experiment 2 records were taken from 480 male and female ducks of an experimental line from day 21 to 45. The birds were raised in groups on deep litter (straw). Commercial pelleted feed and water were provided ad libitum. The distance between feeders and drinkers was 1 m in experiment 1 and 5 m in experiment 2. The following traits were extracted from the records: Number of meals per day (defined as visits to the feeder with feed intake) Duration of meals (sec.) Size of meals (grams.) Intensity of feeding (feed intake in grams. per min): feed intake per meal in relation to duration of meal Duration of pauses (sec. or min.) Duration of feed intake per day (min.) Feed intake per day (grams.) Live weight (grams.) Dates of a total of 530 ducks and containing 260000 visits to the feeder were recorded and analysed On the basis of the duration of the frequency of meals per day two distinct groups, birds with large number of short meals (HM), and birds with a small number of big meals (LM), were identified. Comparisons were made between the two meal-type groups for all traits and the circadian rhythms of feed intake. HM ducks were characterised by short duration and small size of meals, and short pauses between meals. There was only a small difference between the meal-types for the total duration of feeding and feeding intensity. HM birds were lighter than LM birds. With increasing age, number of meals per day and duration of feeding per day decreased while daily feed consumption increased. Duration and size of meals, and intensity of feeding increased with age. Changes in feeding activities were most important between 3 and 4 weeks of age. An effect of sex was only noted for the number of meals at seven weeks of age. Differences in the occurrence of pauses were found in response to the experiment, meal-type and age. With regard to the presentation and analysis of pauses the usual procedures using log survivorship functions were discussed. In the present study, however, the differences in the distribution of pauses have been demonstrated using the relative frequency for the pauses of long duration and the cumulative frequency for the pauses of shorter duration. With regard to the high variation of the duration of pauses among individuals and with age the calculation of a single meal criterion, which separates pauses within and between meals, for all individuals and over all ages was not considered useful. On the basis of the distribution of pauses of the different meal-types it seems that the meal criterion is less than one minute in the HM types, and over 35 minutes in the LM types. The circadian rhythm of feed intake was similar in both meal-type groups and shows a biphasic shape with maxima at the beginning and the end of the light period. There was also feed intake during the dark period, the consumption, however, was lower than in the light period. The power spectra of the feed intake showed main components in the 24; 12; 6 and 4.8 hours rhythms and, in addition, various different rhythms in the area of 2-4 hours. The rhythm pattern was more pronounced in the HM types as compared to the LM types. The power of the 24 hours rhythms decreased with age, while a 6 hours rhythm developed at the end of the test period. In general it can be said, that there are distinct types of temporal structures in feeding behaviour in ducks. Age-depending changes appear mainly in the early fattening phase up to 5 weeks of age. There is no general meal criterion in ducks which may be applied to all individuals and at all ages. Feed intake underlies rhythmic processes which are modified with age.