Identification of new microfoci and genetic characterization of tick-borne encephalitis virus isolates from Eastern Germany and Western Poland

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dc.contributor.authorKról, Nina
dc.contributor.authorChitimia-Dobler, Lidia
dc.contributor.authorDobler, Gerhard
dc.contributor.authorKiewra, Dorota
dc.contributor.authorCzułowska, Aleksandra
dc.contributor.authorObiegala, Anna
dc.contributor.authorZajkowska, Joanna
dc.contributor.authorJuretzek, Thomas
dc.contributor.authorPfeffer, Martin
dc.date.accessioned2024-08-19T12:58:24Z
dc.date.available2024-08-19T12:58:24Z
dc.date.issued2024de
dc.description.abstract(1) Background: Tick-borne encephalitis (TBE) is the most important tick-borne viral disease in Eurasia, although effective vaccines are available. Caused by the tick-borne encephalitis virus (TBEV, syn. Orthoflavivirus encephalitidis), in Europe, it is transmitted by ticks like Ixodes ricinus and Dermacentor reticulatus. TBEV circulates in natural foci, making it endemic to specific regions, such as southern Germany and northeastern Poland. Our study aimed to identify new TBEV natural foci and genetically characterize strains in ticks in previously nonendemic areas in Eastern Germany and Western Poland. (2) Methods: Ticks were collected from vegetation in areas reported by TBE patients. After identification, ticks were tested for TBEV in pools of a maximum of 10 specimens using real-time RT-PCR. From the positive TBEV samples, E genes were sequenced. (3) Results: Among 8400 ticks from 19 sites, I. ricinus (n = 4784; 56.9%) was predominant, followed by D. reticulatus (n = 3506; 41.7%), Haemaphysalis concinna (n = 108; 1.3%), and I. frontalis (n = 2; <0.1%). TBEV was detected in 19 pools originating in six sites. The phylogenetic analyses revealed that TBEV strains from Germany and Poland clustered with other German strains, as well as those from Finland and Estonia. (4) Conclusions: Although there are still only a few cases are reported from these areas, people spending much time outdoors should consider TBE vaccination.en
dc.identifier.urihttps://hohpublica.uni-hohenheim.de/handle/123456789/16072
dc.identifier.urihttps://doi.org/10.3390/v16040637
dc.language.isoengde
dc.rights.licensecc_byde
dc.source1999-4915de
dc.sourceViruses; Vol. 16, No. 4 (2024) 637de
dc.subjectTick-borne encephalitis
dc.subjectOrthoflavivirus encephalitidis
dc.subjectTicks
dc.subjectIxodes ricinus
dc.subjectDermacentor reticulatus
dc.subjectPatients
dc.subjectNonendemic
dc.subjectMicrofocus
dc.subject.ddc610
dc.titleIdentification of new microfoci and genetic characterization of tick-borne encephalitis virus isolates from Eastern Germany and Western Polanden
dc.type.diniArticle
dcterms.bibliographicCitationViruses, 16 (2024), 4, 16072. https://doi.org/10.3390/v16040637. ISSN: 1999-4915
dcterms.bibliographicCitation.issn1999-4915
dcterms.bibliographicCitation.issue4
dcterms.bibliographicCitation.journaltitleViruses
dcterms.bibliographicCitation.volume16
local.export.bibtex@article{Król2024, url = {https://hohpublica.uni-hohenheim.de/handle/123456789/16072}, doi = {10.3390/v16040637}, author = {Król, Nina and Chitimia-Dobler, Lidia and Dobler, Gerhard et al.}, title = {Identification of new microfoci and genetic characterization of tick-borne encephalitis virus isolates from Eastern Germany and Western Poland}, year = {2024}, journal = {Viruses}, volume = {16}, number = {4}, }
local.export.bibtexAuthorKról, Nina and Chitimia-Dobler, Lidia and Dobler, Gerhard et al.
local.export.bibtexKeyKról2024
local.export.bibtexType@article

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