High-resolution association mapping with libraries of immortalized lines from ancestral landraces

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dc.contributor.authorWürschum, Tobias
dc.contributor.authorWeiß, Thea M.
dc.contributor.authorRenner, Juliane
dc.contributor.authorFriedrich Utz, H.
dc.contributor.authorGierl, Alfons
dc.contributor.authorJonczyk, Rafal
dc.contributor.authorRömisch-Margl, Lilla
dc.contributor.authorSchipprack, Wolfgang
dc.contributor.authorSchön, Chris-Carolin
dc.contributor.authorSchrag, Tobias A.
dc.contributor.authorLeiser, Willmar L.
dc.contributor.authorMelchinger, Albrecht E.
dc.date.accessioned2024-09-03T13:38:06Z
dc.date.available2024-09-03T13:38:06Z
dc.date.issued2021de
dc.description.abstractLandraces are traditional varieties of crops that present a valuable yet largely untapped reservoir of genetic variation to meet future challenges of agriculture. Here, we performed association mapping in a panel comprising 358 immortalized maize lines from six European Flint landraces. Linkage disequilibrium decayed much faster in the landraces than in the elite lines included for comparison, permitting a high mapping resolution. We demonstrate this by fine-mapping a quantitative trait locus (QTL) for oil content down to the phenylalanine insertion F469 in DGAT1-2 as the causal variant. For the metabolite allantoin, related to abiotic stress response, we identified promoter polymorphisms and differential expression of an allantoinase as putative cause of variation. Our results demonstrate the power of this approach to dissect QTL potentially down to the causal variants, toward the utilization of natural or engineered alleles in breeding. Moreover, we provide guidelines for studies using ancestral landraces for crop genetic research and breeding.en
dc.identifier.swb1777624789
dc.identifier.urihttps://hohpublica.uni-hohenheim.de/handle/123456789/16514
dc.identifier.urihttps://doi.org/10.1007/s00122-021-03963-3
dc.language.isoengde
dc.rights.licensecc_byde
dc.source1432-2242de
dc.sourceTheoretical and applied genetics; Vol. 135, No. 1 (2021), 243-256de
dc.subjectGenetic variation
dc.subjectDGAT1-2
dc.subjectMaize (Zea mays)
dc.subjectAssociation mapping
dc.subject.ddc630
dc.titleHigh-resolution association mapping with libraries of immortalized lines from ancestral landracesen
dc.type.diniArticle
dcterms.bibliographicCitationTheoretical and applied genetics, 135 (2021), 1,243-256. https://doi.org/10.1007/s00122-021-03963-3. ISSN: 1432-2242
dcterms.bibliographicCitation.issn1432-2242
dcterms.bibliographicCitation.issue1
dcterms.bibliographicCitation.journaltitleTheoretical and applied genetics
dcterms.bibliographicCitation.volume135
local.export.bibtex@techreport{Würschum2021, url = {https://hohpublica.uni-hohenheim.de/handle/123456789/16514}, doi = {10.1007/s00122-021-03963-3}, author = {Würschum, Tobias and Weiß, Thea M. and Renner, Juliane et al.}, title = {High-resolution association mapping with libraries of immortalized lines from ancestral landraces}, journal = {Theoretical and applied genetics}, year = {2021}, volume = {135}, number = {1}, }
local.export.bibtexAuthorWürschum, Tobias and Weiß, Thea M. and Renner, Juliane et al.
local.export.bibtexKeyWürschum2021
local.export.bibtexType@techreport

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