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Doctoral Thesis
2025
Mineral bioaccessibility and safety assessment of plant-based meat alternatives and targeted enrichment of essential nutrients in a cultured meat cell line model
Mineral bioaccessibility and safety assessment of plant-based meat alternatives and targeted enrichment of essential nutrients in a cultured meat cell line model
Abstract (English)
Plant-based meat alternatives (PBMA) and cultured meat have gained recognition as substitutes for conventional meat, and their consumption is expected to increase due to the limited sustainability of traditional meat production systems. Meat is a source of bioaccessible iron and zinc for the general population. Replacing it with plant-based substitutes requires ensuring adequate nutrient intake. However, PBMA are formulated using various plant-based ingredients, leading to substantial variations in nutrient content that can significantly affect the mineral bioaccessibility. Consequently, the replacement of meat with PBMA may influence the intake and status of these minerals at both individual and population levels. Moreover, the preparation of PBMA through pan-frying at temperatures exceeding 120 degrees celsius may lead to the formation of Maillard reaction products, including acrylamide and furanoic compounds, which may pose health risks when consumed in higher amounts. Consequently, this doctoral thesis assessed the bioaccessibility of iron and zinc from commercially available PBMA and investigated the formation of acrylamide and furanoic compounds during pan-frying at different temperatures. The results demonstrated that the PBMA analyzed did not pose a significant health risk to consumers due to their low concentrations of acrylamide and furanoic compounds after pan-frying. In addition, it was shown that even though the bioaccessibility of iron and zinc was impaired by the presence of absorption inhibitors, such as phytate, commercially available PBMA can still contribute to meet the daily recommendations of iron and zinc.
The second part of the thesis explored the potential for enriching health-promoting compounds in a cultured meat cell model. A notable finding was the significant accumulation of the omega-3 fatty acid alpha-linolenic acid and ferrous sulfate (iron) without inducing lipid peroxidation, which highlights the potential of targeted enrichment strategies to enhance the nutritional profile of cultured meat, offering a promising approach for the development of healthier and more sustainable meat alternatives.
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Faculty
Faculty of Natural Sciences
Institute
Institute of Nutritional Sciences
Examination date
2025-11-27
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Cite this publication
Pospiech, J. (2025). Mineral Bioaccessibility and Safety Assessment of Plant-Based Meat Alternatives and Targeted Enrichment of Essential Nutrients in a Cultured Meat Cell Line Model. https://doi.org/10.60848/13434
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Language
English
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Classification (DDC)
500 Science
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University bibliography
Standardized keywords (GND)
Sustainable Development Goals
BibTeX
@phdthesis{Pospiech2025-11-27,
url = {https://hohpublica.uni-hohenheim.de/handle/123456789/18504},
author = {Pospiech, Jonas},
title = {Mineral Bioaccessibility and Safety Assessment of Plant-Based Meat Alternatives and Targeted Enrichment of Essential Nutrients in a Cultured Meat Cell Line Model},
year = {2025-11-27},
}