A new version of this entry is available:
Loading...
Article
2021
Interrelationship of myo-inositol pathways with systemic metabolic conditions in two strains of high-performance laying hens during their productive life span
Interrelationship of myo-inositol pathways with systemic metabolic conditions in two strains of high-performance laying hens during their productive life span
Abstract (English)
Adaptation to metabolic challenges is an individual process in animals and human, most likely based on genetic background. To identify novel pathways of importance for individual adaptation to a metabolic challenge such as egg production in laying hens, myo-inositol (MI) metabolism and plasma metabolite profiles during the productive lifespan were examined in two genetically different strains, Lohmann Brown-Classic (LB) and LSL-Classic (LSL) hens. They were housed during the productive lifespan and sampled at 10, 16, 24, 30 and 60 weeks of age. The targeted AbsoluteIDQ p180 Kit was used for metabolite profiling in plasma whereas a MI enzymatic kit and ELISAs were used to quantify tissue MI concentrations and MI key enzymes (IMPase 1 and MIOX), respectively. As major finding, kidney MIOX was differently expressed in LB and LSL hens with higher amounts in LB. The onset of egg laying between week 16 and 24 of life span was associated with a clear change in the metabolite profiles, however LSL hens and LB hens adapt differently. Pearson’s correlation analyses over all hens at all time points indicated that higher expression of MI degrading enzyme MIOX was related to markers indicating metabolic stress.
File is subject to an embargo until
This is a correction to:
A correction to this entry is available:
This is a new version of:
Other version
Notes
Publication license
Publication series
Published in
Scientific reports, 11 (2021), 4641.
https://doi.org/10.1038/s41598-021-84169-x.
ISSN: 2045-2322
Other version
Faculty
Institute
Examination date
Supervisor
Cite this publication
Gonzalez-Uarquin, F., Sommerfeld, V., Rodehutscord, M., & Huber, K. (2021). Interrelationship of myo-inositol pathways with systemic metabolic conditions in two strains of high-performance laying hens during their productive life span. Scientific reports, 11. https://doi.org/10.1038/s41598-021-84169-x
Edition / version
Citation
DOI
ISSN
ISBN
Language
English
Publisher
Publisher place
Classification (DDC)
630 Agriculture
Collections
Original object
University bibliography
Free keywords
Standardized keywords (GND)
Sustainable Development Goals
BibTeX
@article{Gonzalez-Uarquin2021,
url = {https://hohpublica.uni-hohenheim.de/handle/123456789/16401},
doi = {10.1038/s41598-021-84169-x},
author = {Gonzalez-Uarquin, Fernando and Sommerfeld, Vera and Rodehutscord, Markus et al.},
title = {Interrelationship of myo-inositol pathways with systemic metabolic conditions in two strains of high-performance laying hens during their productive life span},
journal = {Scientific reports},
year = {2021},
volume = {11},
}